Molecularly imprinted microspheres prepared by precipitation polymerization at high monomer concentrations

Peptide-imprinted polymer microspheres prepared by precipitation polymerization using a single bi-functional monomer.

A single bi-functional monomer, N,O-bismethacryloyl ethanolamine (NOBE), was used in precipitation polymerization system to synthesize molecularly imprinted polymer (MIP) microspheres. Highly specific binding sites were obtained for N-terminal protected neuropeptides, Boc-Leu-enkephalin and Pyr-Leu-enkephalin. The use of NOBE allowed binding sites to be formed in polymer microspheres that are a...

In silico design for synthesis of molecularly imprinted microspheres specific towards bisphenol A by precipitation polymerization

Bisphenol A (BPA), a ubiquitous chemical used in industries, has attracted great attention due to its widespread leakage to the environment and foodstuff. This has spurred great interest in the preparation of synthetic polymers capable of selectively sequestering BPA. In this study, theoretical calculation was utilized to confirm the selection of suitable functional monomer capable of strong in...

Preparation and characterization of monodisperse molecularly imprinted polymer microspheres by precipitation polymerization for kaempferol

A new kind of molecularly imprinted polymer (MIP) microspheres for the selective extraction of kaempferol was prepared by precipitation polymerization using 4-vinylpridine (4-VP) and ethylene glycol dimethacrylate (EDMA) as functional monomer and cross-linker respectively. The synthesis conditions, such as ratios of 4-VP/EDMA and polymerization time were discussed in detail. Results showed that...

Molecularly imprinted polymer beads for nicotine recognition prepared by RAFT precipitation polymerization: a step forward towards multifunctionalities

Separation of Cholesterol from Other Steroids Using Molecularly Imprinted Polymer Prepared by Seeded Suspension Polymerization

Micron-sized particles of cholesterol-imprinted polymers were synthesized by seeded suspension polymerization in a mixture of 2-propanol and water using polystyrene microbeads as the seeds. Methacrylic acid was employed as the functional monomer to form complexes with template (cholesterol), along with ethylene glycol dimethacrylate as the crosslinker. After removal of template molecules, the c...